MALIGNANT HISTIOCYTOSIS: A CASE REPORT AND REVIEW OF THE LITERATURE

Authors

  • A BANIHASHEM From the Departments of Pediatrics Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Islamic Republic of Iran.
  • S ZABIHYAN
  • T GHIASSI From the Departments of Pathology, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Islamic Republic of Iran.
Abstract:

Malignant histiocytosis (MH) is a rare hematologic malignancy, especially in the first decade of life. The disease is clinically characterized by fever, hepatosplenomegaly, lymphadenopathy, pancytopenia and jaundice, and histologically by systemic proliferation of malignant histiocytes and hemophagocytosis. The prognosis is poor and often the diagnosis is not made before death. Because of the rarity of this disease, it is unusual for practitioners to diagnose it by bone marrow aspiration (BMA) alone

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Journal title

volume 10  issue 1

pages  79- 83

publication date 1996-05

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